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Su acci n en Chiapas fracas no s lo
2019-05-28

Su acción en Chiapas fracasó, no sólo por el rechazo que generó entre los encomenderos sino también entre los religiosos que apoyaban la encomienda en beneficio propio o bien como mecanismo de cristianización acelerado. Cuando Las Casas regresa p-Cresyl sulfate España, en lo que hace a su batalla de
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Subalternidad y contras Nuestra lectura
2019-05-28

Subalternidad y “contras” Nuestra lectura está enmarcada por principios teóricos retomados de los Estudios Subalternos. Identificamos mpges-1 inhibitors los campesinos, especialmente a los participantes en las guerras civiles, como subalternos. Interpretamos que las formas en que se representa e in
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La no intervenci n en
2019-05-28

La no intervención en los asuntos de otro Estado no significa indiferencia ante los problemas que éste pueda tener. En efecto, algunos usos y gestiones pueden perjudicar in the morning países vecinos y también al mismo Estado que las realiza. Es por esto que la soberanía no resulta absoluta en lo qu
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rsv Jes s estigmatiz en su predicaci n la injusticia social
2019-05-28

“Jesús estigmatizó en su predicación la injusticia social de su tiempo” y lo hizo sin compasión, decía Cullmann. “Jesús anuncia que, a la luz del Reino que ha de venir, la diferencia entre ricos y pobres es contraria a la voluntad divina. Ese juicio sobre el orden social presente es, de suyo, revolu
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La nueva escritura del Quijote que emprende
2019-05-28

La nueva escritura del Quijote que emprende Menard resulta a la vez, en gran paradoja, la más fiel y la más infiel, la transcripción total y la adaptación libérrima, y llega incluso a la reducción al absurdo de las leyes del homenaje literario: especie de homenaje por sus antípodas, ya que se omite
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br It is encouraging to
2019-05-28

It is encouraging to read in the Article by Mercy Kanyuka and colleagues (March, 2016) about Malawi\'s success in reducing child mortality, but I fear the authors might have missed one of the key factors contributing towards this great achievement. Specifically, that Malawi is unique in sub-Sahara
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br From a historical perspective Professional
2019-05-28

From a historical perspective, Professional Medical Associations (PMAs) were developed as groups with a shared scientific interest or established by the authorities to act as a regulatory body. PMAs have different roles based on which country they somatostatin agonist are located in and the healt
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Obesity with excessive fat was an important risk
2019-05-28

Obesity with excessive fat was an important risk factor for the occurrence or progression of cardiac arrhythmia. As compared to abdominal fat, the amount of epicardial fat more correlates with the occurrences of atrial fibrillation, which suggests the distinctive arrhythmogenic effects of epicardial
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VV optimization From the foregoing
2019-05-28

VV optimization From the foregoing discussion, it is clear that AV delay programming to ensure ventricular preexcitation with optimal LV diastolic filling and systolic function is complex, and the optimal method that translates into improved patient outcomes is uncertain. These issues are even more
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We herein report a patient with dMMR and MSI H
2019-05-28

We herein report a patient with dMMR and MSI-H metastatic gastric cancer who buy AZD 0530 responded favorably and durably to PD-1 blockade. This patient, along with the previous two demonstrated by Le et al, are up-to-date the only 3 MMR gastric cancer patients who responded well to PD-1 blockade. R
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Preference for injectable therapy over oral therapy contrary
2019-05-28

Preference for injectable therapy over oral therapy [17], contrary to our findings from a previous study [18], could reflect the fact that most patients have not received an oral bone-targeted agent for metastatic disease. However, the practical advantages of an injectable therapy and the lack of ne
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Introduction Despite advances in the treatment of early stag
2019-05-28

Introduction Despite advances in the treatment of early stage breast cancer, bone remains the most common site of distant poly ic [1]. The consequences of bone metastases include reduced survival, morbidity, pain and reduced quality of life [2]. While the care of these patients is multidisciplinary
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CaMKII phosphorylation of L type Ca
2019-05-27

CaMKII phosphorylation of L-type Ca2+channels alters channel gating by increasing open probability. CaMKII increases the window current of ICa-L, increasing the probability of the channels reopening during phase 2 train ride and predisposing to early afterdepolarizations. Recently identified phospho
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All these receptors tightly control tissue homeostasis and a
2019-05-27

All these receptors tightly control tissue homeostasis, and any dysregulation of these ligand–receptor systems (mutations, overexpression, etc.) disturbs cell communication and leads to pathological situations. Bone formation and bone remodelling are then controlled by a large panel of cytokines and
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In addition to inducing IKs
2019-05-27

In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor
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